Positive Result in the Early Passive Phase of the Tilt-table Test: A Predictor of Neurocardiogenic Syncope in Young Men.
10.3904/kjim.2012.27.1.60
- Author:
Jae Sun UHM
1
;
Ho Joong YOUN
;
Woo Baek CHUNG
;
Yun Seok CHOI
;
Chul Soo PARK
;
Yong Seog OH
;
Wook Sung CHUNG
;
Kyung Il PARK
;
Tae Suk KIM
Author Information
1. Division of Cardiology, Department of Internal Medicine, The Catholic University of Korea School of Medicine, Seoul, Korea. younhj@catholic.ac.kr
- Publication Type:Original Article
- Keywords:
Syncope, vasovagal;
Prognosis;
Tilt-table test
- MeSH:
Adolescent;
Adult;
Age Factors;
Humans;
Logistic Models;
Male;
Multivariate Analysis;
Predictive Value of Tests;
Prognosis;
Prospective Studies;
Recurrence;
Republic of Korea;
Sex Factors;
Syncope, Vasovagal/*diagnosis/physiopathology;
*Tilt-Table Test;
Time Factors;
Young Adult
- From:The Korean Journal of Internal Medicine
2012;27(1):60-65
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND/AIMS: This study elucidated the prognostic factors for neurocardiogenic syncope in males in their late teens and early twenties. METHODS: Tilt-table testing (TTT) was performed on 665 males (age range, 17 to 27 years) following the Italian protocol. The subjects were tilted head-up at a 70degrees angle on a table for 30 minutes during the passive phase. If the passive phase was negative, the subjects were given sublingual nitroglycerin and tilted to the same angle for 20 minutes during the drug-provocation phase. The subjects with positive results were followed without medication. We analyzed factors related to the recurrence rate of syncope. RESULTS: Of 305 subjects (45.8%) with positive results, 223 (age range, 18 to 26 years) were followed for 12 months. The frequency of previous syncopal episodes > or = 4 (p = 0.001) and a positive result during the passive phase (p = 0.022) were significantly related to a high recurrence rate. A positive result during the early passive phase (< or = 12 minutes) was significantly related to a higher recurrence rate than was that during the late passive phase (> 12 minutes; p = 0.011). CONCLUSIONS: A positive result during the early passive phase of TTT and frequent previous syncopal episodes were prognostic factors for neurocardiogenic syncope in men in their late teens and early twenties.