Malignant Adenomyoepithelioma of the Breast.
- Author:
Min Ho PARK
1
Author Information
1. Department of Surgery, Chonnam National University Medical School, Gwangju, Korea. thokthok@hanmail.net
- Publication Type:Case Report
- Keywords:
Breast;
Malignant;
Adenomyoepithelioma
- MeSH:
Actins;
Adenomyoepithelioma*;
Adult;
Breast*;
Epithelial Cells;
Female;
Humans;
Keratins;
Myoepithelioma
- From:Journal of the Korean Surgical Society
2007;73(5):430-433
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
An adenomyoepithelioma of the breast is an uncommon tumor that is characterized by biphasic lesions, which consist of epithelial and myoepithelial cells. Most adenomyoepitheliomas are benign, and a malignant transformation is rare. It is generally limited to the epithelial component but in rare cases, the myoepithelial component may become malignant and give rise to a malignant myoepithelioma. We encountered a case of a 29-year-old woman who presented with both an epithelial and myoepithelial carcinoma of the breast in an adenomyoepithelioma. The malignancy was evidenced by the presence of pleomorphism, a high mitotic rate and local invasion. Immunohistochemical staining demonstrated the expression of cytokeratin in epithelial cells and actin in myoepithelial cells. We report this case of a malignant adenomyoepithelioma of the breast with review of the relevant literature.
