Two Cases of Generalized Vitiligo after Allogeneic Stem Cell Transplantation.
- Author:
Yeo Kyeoung KIM
1
;
Deok Hwan YANG
;
Jeoung Rae BYUN
;
Sang Hee CHO
;
Je Jung LEE
;
Hyeoung Joon KIM
;
Yang An KIM
;
Seung Hoon CHA
Author Information
1. Department of Internal Medicine, Chonnam National University Medical School, Gwangju, Korea.
- Publication Type:Case Report
- Keywords:
Vitiligo;
Allogeneic stem cell transplantation;
Narrow band ultraviolet therapy
- MeSH:
Anemia, Aplastic;
Autoimmune Diseases;
Bone Marrow;
Bone Marrow Transplantation;
Humans;
Leukemia;
Peripheral Blood Stem Cell Transplantation;
Siblings;
Stem Cell Transplantation*;
Stem Cells*;
Tissue Donors;
Vitiligo*
- From:Korean Journal of Dermatology
2005;43(5):660-664
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Generalized vitiligo associated with allogeneic bone marrow or stem cell transplantation has rarely been reported. We experienced two cases of generalized vitiligo after allogeneic bone marrow and stem cell transplantation. The first patient was received an allogeneic bone marrow transplantation and subsequent allogeneic peripheral blood stem cell transplantation for severe aplastic anemia from his sister. The second patient underwent allogeneic bone marrow transplantation for acute myelogeneous leukemia from his sister. Generalized vitiligo developed after transplantation. Neither vitiligo nor evidences of autoimmune diseases were found in their stem cell donors. Vitiligo was effectively treated with narrow band UVB irradiation.