The Change in Distribution of Red Blood Cell Antigens in Korean Youth: In an Era of Multicultural Society.
10.17945/kjbt.2016.27.2.105
- Author:
Kyung Hwa SHIN
1
;
Hyung Hoi KIM
;
Hyun Ji LEE
;
Tae Young AHN
;
Kyoung Un PARK
;
Yun Ji HONG
;
Jeong Ran KWON
;
Young Sill CHOI
;
Jun Nyun KIM
Author Information
1. Department of Laboratory Medicine, Pusan National University Hospital, Busan, Korea. hhkim@pusan.ac.kr
- Publication Type:Original Article
- Keywords:
Blood group antigens;
Rh-Hr blood Group system;
Korea
- MeSH:
Adolescent*;
Blood Group Antigens;
Blood Transfusion;
Emigrants and Immigrants;
Erythrocytes*;
Humans;
Korea
- From:Korean Journal of Blood Transfusion
2016;27(2):105-112
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: It is important to check the blood group antigens to ensure the safety of blood transfusions. Recently, the number of multicultural families and foreigners has increased in Korea; therefore, a survey for red blood cell antigens for multicultural families is need. We performed a phenotyping of their red blood cell antigens and found the characteristics in providing basic data. METHODS: We recruited young people under the age of 26 years from multicultural family between September 2015 and March 2016. The participants were divided into two groups: the multicultural youth group (MCY) and the non-multicultural youth group (non-MCY). Subjects underwent phenotyping of ABO, Rh, Kell, Kidd, Duffy, MNS, and Diego blood group, and the results were compared and characterized between the two groups. RESULTS: A total of 226 subjects (89 MCY, 137 non-MCY) were recruited. The blood groups with differences between MCY and non-MCY were E, e in Rh and S in MNS. In MCY, the frequency of CDe expression in the Rh blood group was higher and the cDE expression was lower. There were 3.4% and 2.2% of MCY with no expression of Fy(a) and s, respectively, which were rare blood types in Koreans. CONCLUSION: The difference in frequency of red blood cell antigens between MCY and non-MCY have been identified. These results suggest that the national blood policy reflects an increasing number of multicultural families and Korea needs to be prepared for a population change.
