GRA Proteins of Toxoplasma gondii: Maintenance of Host-Parasite Interactions across the Parasitophorous Vacuolar Membrane.
10.3347/kjp.2009.47.S.S29
- Author:
Ho Woo NAM
1
Author Information
1. Department of Parasitology, College of Medicine, The Catholic University of Korea, Seoul 137-701, Korea. howoo@catholic.ac.kr
- Publication Type:Review
- Keywords:
Toxoplasma gondii;
dense granule;
GRA protein;
PVM;
host-parasite interaction
- MeSH:
Animals;
Antigens, Protozoan/*metabolism;
Cytoplasmic Granules/metabolism;
*Host-Parasite Interactions;
Humans;
Protozoan Proteins/*metabolism;
Toxoplasma/*metabolism;
Toxoplasmosis/*parasitology;
Vacuoles/*metabolism
- From:The Korean Journal of Parasitology
2009;47(Suppl):S29-S37
- CountryRepublic of Korea
- Language:English
-
Abstract:
The dense granule of Toxoplasma gondii is a secretory vesicular organelle of which the proteins participate in the modification of the parasitophorous vacuole (PV) and PV membrane for the maintenance of intracellular parasitism in almost all nucleated host cells. In this review, the archives on the research of GRA proteins are reviewed on the foci of finding GRA proteins, characterizing molecular aspects, usefulness in diagnostic antigen, and vaccine trials in addition to some functions in host-parasite interactions.
