The Results of Radiation Therapy in Locally Advanced Non-Small Cell Lung Cancer.
- Author:
Mi Sook KIM
1
;
Seoung Yul YOO
;
Chul Koo CHO
;
Jae Young KIM
;
Jae Won SHIM
;
Choon Taek LEE
;
Yoon Koo KANG
;
Tae You KIM
Author Information
1. Department of Radiation Oncology, Korea Cancer Center Hospital, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Non-small cell cancer;
Radiation therapy;
Prognostic factor
- MeSH:
Brain;
Carcinoma, Non-Small-Cell Lung*;
Chemoradiotherapy;
Drug Therapy;
Follow-Up Studies;
Humans;
Liver;
Lung;
Lymph Nodes;
Multivariate Analysis;
Neoplasm Metastasis;
Pathology;
Radiotherapy;
Retrospective Studies;
Survival Rate
- From:Journal of the Korean Society for Therapeutic Radiology
1997;15(3):233-242
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: This study was done to evaluate the survival rate and prognostic factors of patients with inoperable non-small cell lung cancer (NSCLC) treated with radiation therapy. MATERIALS AND METHODS: A retrospective analysis was undertaken of 62 patients who had inoperable NSCLC treated with radiation therapy from January 1991 through December 1993. According to AJCC staging, stage III A was 14 patients and stage IIIB was 48 patients. Forty Gy to 70.2Gy to the primary tumor site was delivered with daily fractions of 1.8Gy or 2Gy, 5 days per week. Thirty-seven patients received neoadjuvant chemotherapy. RESULTS: Complete, partial and no response to radiation therapy were 3 patients, 34 patients and 25 patients, respectively. The median survival period of all patients was 11 month. One year survival rate, 2 year survival rate and 5 year survival rate for all patients were 45.0%, 14.3%, and 6.0% respectively. The median survival period was 6.5 months in stage IIIA and 13 months in stage IIIB. One year survival rates were 28.6% in stage IIIA and 50.3% in stage IIIB. In univariaite analysis, prognostic factors affecting survival were T-staging, AJCC staging, and response after radiation therapy (P<0.05). Pretreatment peformance status affected survival but was not statistically significant (0.05
