An Experimental Study for Minimum Level of Decalcification to Detect the Osteolytic Bone Metastasis of Long Bone on Plain Radiography.
10.11005/jbm.2016.23.3.135
- Author:
Jun Ho BAEK
1
;
Il Hyung PARK
;
Sung Hwa SEO
Author Information
1. Department of Orthopaedic Surgery, Kyungpook National University Hospital, Daegu, Korea. ihpark@knu.ac.kr
- Publication Type:Original Article
- Keywords:
Bone metastasis;
Decalcification technique;
Osteolysis;
Radiography
- MeSH:
Cadaver;
Calcium;
Decalcification Technique;
Fibula;
Humerus;
Neoplasm Metastasis*;
Osteolysis;
Radiographic Image Enhancement;
Radiography*
- From:Journal of Bone Metabolism
2016;23(3):135-142
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND: In 1951, Ardran reported that metastatic bone lesions could be detectable on plain radiography with 30% to 50% of decalcification. Authors performed experimental study for minimum level of decalcification to detect the osteolytic bone metastasis of long bone with recent technique of radiographs. METHODS: One pair of fibula and humerus from two cadavers was cut into specimen 1 inch in length. Distal half of specimen was dipped into hydrochloride (HCl) with 15 min interval. All 16 specimens were checked by film-type radiography (FR), computed radiography (CR), digital radiography (DR). To exclude inter-observer's variance, 3 radiologists evaluated images. Calcium amount before and after decalcification was measured and expressed in percentage of decalcification. RESULTS: Osteolytic changes were detectable with 11% to 16% of decalcification for fibula and 3% to 8% for humerus on plain radiography with FR, CR, and DR. CONCLUSIONS: Our study showed that minimum of 3% and maximum of 16% of decalcification is necessary when osteolytic metastatic bone lesions of long bone could be detected on plain radiography.
