The Usefulness of a Colonoscopy with Biopsy in the Early and Accurate Diagnosis of Ischemic Colitis.
- Author:
Eui Joong KIM
1
;
Soon Man YOON
;
Sang Hwa LEE
;
Ki Bae KIM
;
Joo Young LEE
;
Dong Hwa LEE
;
Eun Bee KIM
;
Soonyoung PARK
;
Joung Ho HAN
;
Hee Bok CHAE
;
Seon Mee PARK
;
Sei Jin YOUN
;
Ro Hyun SUNG
Author Information
- Publication Type:Original Article
- Keywords: Ischemic colitis; Colonoscopy; Biopsy; Diagnosis
- MeSH: Abdominal Pain; Arrhythmias, Cardiac; Atrophy; Biopsy; Capillaries; Colitis; Colitis, Ischemic; Colon; Colonoscopy; Diarrhea; Gastrointestinal Hemorrhage; Hemorrhage; Humans; Hypertension; Mucous Membrane; Necrosis
- From:Intestinal Research 2013;11(2):100-106
- CountryRepublic of Korea
- Language:Korean
- Abstract: BACKGROUND/AIMS: Ischemic colitis has a clinical spectrum ranging from mild reversible colitis to an acute fulminant course. Early and accurate diagnosis is therefore mandatory for a good clinical outcome. The aim of this study is to evaluate the efficacy and safety of a colonoscopy and histological examination with biopsy in the early and accurate diagnosis of ischemic colitis. METHODS: We investigated the clinical characteristics and endoscopic findings with the histopathology of 89 cases of ischemic colitis from October 2002 to August 2012 in a tertiary-care hospital. All patients underwent a colonoscopy with biopsy within a few days of the onset of symptoms, and the histological features from the biopsy specimens were reviewed. In addition, the occurrence of complications by colonoscopy with biopsy was evaluated. RESULTS: The mean age of the patients was 65.8+/-12.6 years (male:female, 1:2.2). The major combined disorders were hypertension (51.7%), diabetes (31.5%), and arrhythmia (19.1%). The clinical features usually presented with hematochezia (83.1%), abdominal pain (77.5%), and diarrhea (60.7%). The involved patterns were the left colon (56.2%), right colon (39.3%), and pancolon (4.5%). Based on the main histological features of ischemic colitis, including glandular atrophy (67.4%), hemorrhage (61.8%), capillary thrombi (42.7%), and coagulative necrosis of mucosa (29.2%), 67 of the 89 cases (75.3%) could be confirmed with ischemic colitis. There were no serious complications such as bowel perforation or major bleeding following the colonoscopy with biopsy. CONCLUSIONS: A colonoscopy with biopsy is beneficial and safe for the early and precise diagnosis of ischemic colitis.
