Clinical Characteristics of Lower Gastrointestinal Cancer in Crohn's Disease: Case Series of 5 Patients.
- Author:
Ji Min CHOI
1
;
Changhyun LEE
;
Yoo Min HAN
;
Minjong LEE
;
Dong Kee JANG
;
Jeehye KWON
;
Jong Pil IM
;
Sang Gyun KIM
;
Joo Sung KIM
;
Hyun Chae JUNG
Author Information
- Publication Type:Case Report
- Keywords: Crohn disease; Jejunal neoplasms; Ileal neoplasms; Colorectal neoplasms
- MeSH: Colorectal Neoplasms; Crohn Disease; Gastrointestinal Neoplasms; Gastrointestinal Tract; Humans; Ileal Neoplasms; Jejunal Neoplasms; Korea
- From:Intestinal Research 2013;11(2):127-133
- CountryRepublic of Korea
- Language:Korean
- Abstract: Crohn's disease is a chronic inflammatory disease that can involve the entire gastrointestinal tract. Several studies indicate that Crohn's patients with long disease duration have an increased risk of small bowel or colorectal cancer. In Korea, only a few cases of Crohn's disease-related small bowel or colorectal cancer have been reported. Here, we described 3 cases of colorectal cancer and 2 cases of small bowel cancer in patients with Crohn's disease. Among 5 patients, 3 had Crohn's disease-related lower gastrointestinal malignancy and the other 2 had sporadic lower gastrointestinal malignancies. Since the diagnosis of Crohn's disease-related lower gastrointestinal malignancy tends to be delayed, the development of malignancy should be considered in patients with long duration of Crohn's disease if patients have refractory symptoms despite intensive medical treatment. Surgical consultation should not be delayed.
