A Case of CATCH22 Syndrome Diagnosed in Postmenopausal Woman.
10.11005/jbm.2013.20.1.57
- Author:
Seung Kyung LEE
1
;
Min Jeong LEE
;
Hyo Jin LEE
;
Bu Kyung KIM
;
Young Bae SOHN
;
Yoon Sok CHUNG
Author Information
1. Department of Endocrinology and Metabolism, Ajou University School of Medicine, Suwon, Korea. yschung@ajou.ac.kr
- Publication Type:Case Report
- Keywords:
Hypocalcemia;
Hypoparathyroidism;
DiGeorge Syndrome
- MeSH:
Ambulatory Care Facilities;
Calcium;
Congenital Abnormalities;
DiGeorge Syndrome;
Female;
Follow-Up Studies;
Humans;
Hypocalcemia;
Hypoparathyroidism;
Kidney;
Kidney Diseases;
Prevalence;
Vitamin D;
Wills
- From:Journal of Bone Metabolism
2013;20(1):57-60
- CountryRepublic of Korea
- Language:English
-
Abstract:
CATCH 22 Syndrome is caused by chromosome 22q11.2 microdeletion, characterized by developmental abnormalities of the third and fourth pharyngeal pouches. It has a prevalence estimated at 1:3,000-1:9,000. Most deletions occurs sporadic, but autosomal dominant inheritance observed in 6-10% of cases. CATCH22 often diagnosed due to hypocalcemia during neonatal period or decreased immunity or facial defect, so it is very rare being diagnosed CATCH22 in adulthood. We report a 57 year old female who referred to mental change due to hypocalcemia and is diagnosed CATCH22. She was presented with hypoparathyroidism, single kidney due to renal agenesis, and mild facial defect. Our patient responded well to calcium and vitamin D treatment and she is on follow-up in outpatient clinic.
