Intestinal Neuronal Dysplasia.
- Author:
Jeong Kee SEO
1
Author Information
1. Division of Gastroenterology, Hepatology and Nutrition, Children's Hospital, Seoul National University College of Medicine, Seoul, Korea. jkseo@snu.ac.kr
- Publication Type:Review ; English Abstract
- Keywords:
Intestinal neuronal dysplasia;
Chronic intestinal pseudo-obstruction;
Hirschsprung's disease
- MeSH:
Child;
Colon/*innervation/radiography;
Constipation/etiology;
Enteric Nervous System/*abnormalities;
Ganglia/pathology;
Gastrointestinal Motility;
Hirschsprung Disease/pathology;
Humans;
Immunohistochemistry;
Intestinal Diseases/*diagnosis/pathology;
Intestinal Mucosa/pathology
- From:The Korean Journal of Gastroenterology
2007;50(3):145-156
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Intestinal neuronal dysplasia (IND) type B is a disease of the submucosal plexus of intestine manifesting chronic intestinal obstruction or severe chronic constipation. IND is one of intestinal dysganglionoses and clinically closely associated with Hirschsprung's disease. Until recently, it is not fully clear whether IND is a congenital malformation or an acquired secondary condition related to some gastrointestinal problems. However, recently published data and consensus reports have enhanced our understanding of the pathogenesis and management of IND. The aim of this paper was to review the current state of knowledge regarding the controversial issues of IND including the etiology, classification, diagnostic criteria, and available therapeutic intervention.
