Isolated Myeloid Sarcoma Presenting as Cord Compression by Paraspinal Mass.
10.12771/emj.2016.39.1.17
- Author:
Hyun Ho OH
1
;
Hyun Jung KIM
;
Tae Hee HAN
;
Min Kwan KWON
;
Soo Ya BAE
;
Young Jin YUH
Author Information
1. Department of Internal Medicine, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea. yjyuh@paik.ac.kr
- Publication Type:Case Report
- Keywords:
Myeloid sarcoma;
Spinal cord compression;
Leukemia
- MeSH:
Aged;
Back Pain;
Bone Marrow;
Cytarabine;
Daunorubicin;
Drug Therapy;
Humans;
Hypesthesia;
Leukemia;
Lower Extremity;
Male;
Myelodysplastic Syndromes;
Sarcoma, Myeloid*;
Spinal Cord Compression
- From:The Ewha Medical Journal
2016;39(1):17-22
- CountryRepublic of Korea
- Language:English
-
Abstract:
Myeloid sarcoma is a rare tumor mass consisting of immature granulocytic cells occurring in an extramedullary site or in a bone. It has often been observed during the course of an acute leukemia, myelodysplastic syndrome or myeloproliferative neoplasms, and it can involve any site of the body. However, it rarely present in the absence of bone marrow infiltration, especially for the isolated spinal myeloid sarcoma. In this report, we describe a case of isolated myeloid sarcoma that showed spinal compression. A 66-year-old male, with no underlying disease or medication history, presented with a progressive back pain and numbness in bilateral lower extremities that had begun two weeks before. He was diagnosed with myeloid sarcoma with no evidence of bone marrow involvement. Tumor cells were positive for CD34, c-KIT, and Bcl-2 on the immunohistochemical stain. He was treated with systemic chemotherapy with daunorubicin plus cytosine arabinoside and achieved a partial response.
