Histomorphological Comparison of the Coronary Artery and Available Graft Conduits.
- Author:
Yong Ho KIM
1
;
Seok Ki LEE
;
Jeong Hwan YU
;
Si Wook KIM
;
Shin Kwang KANG
;
Seung Pyung LIM
;
Jae Hyeon YU
;
Young LEE
Author Information
1. Department of Thoracic and Cardiovascular Surgery, Chungnam National University Hospital, Chungnam National University, College of Medicine, Korea. y_lee@cnu.ac.kr
- Publication Type:Original Article
- Keywords:
Coronary artery bypass conduits;
Histology
- MeSH:
Arteries;
Cadaver;
Coronary Artery Bypass;
Coronary Vessels;
Elastin;
Humans;
Hyperplasia;
Male;
Mammary Arteries;
Radial Artery;
Transplants
- From:The Korean Journal of Thoracic and Cardiovascular Surgery
2008;41(5):563-567
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: The histomorphological properties of the left anterior desecending artery (LAD), the left internal thoracic arteries (LITA), the radial arteries (RA) and the intercostal arteries (ICA) were studied for their use as a conduit for coronary artery bypass grafting (CABG), and we compared them with each other. MATERIAL AND METHOD: All the vessels were harvested from nineteen cadavers (17 males and 2 females). The mid-portion of the LAD, the mid-portion of the LITA, the distal RA and the mid-portion of the 5th ICA were obtained. All of them were stained with hematoxylin-eosin and with Van Gieson's elastin stain. The morphological characteristics were examined and the thicknesses of the intima and media (I/M ratio: the intima to media ratio) were compared using one-way ANOVA tests. RESULT: The mean age of the cadavers was 61.5+/-9.6 years. The LITA and ICA were elastic arteries, and the LAD and RA were muscular arteries. The I/M ratio showed statistically significant differences: 0.07+/-0.03 in the LITA, 0.16+/-0.11 in the ICA, 0.45+/-0.29 in the RA and 0.93+/-0.52 in the LAD, respectively. CONCLUSION: This study showed that the degrees of intimal hyperplasia of the CA and the various conduits for CABG were different significantly. The ICA was found to have relatively favorable characteristics as a coronary bypass conduit, but its suitability for clinical use is a challenging issue.
