The Relationship between Febrile Convulsion and Temporal Lobe Epilepsy: Is Febrile Convulsion a Preferential Association with Temporal Lobe Epilepsy?.
- Author:
Jung Wook JUNG
1
;
Sung Eun KIM
;
Tae Yoon LEE
;
Kyoung HEO
Author Information
1. Department of Neurology, Inje University Pusan Paik Hospital.
- Publication Type:Original Article
- Keywords:
Febrile convulsion;
Temporal lobe epilepsy;
Complex febrile convulsion
- MeSH:
Classification;
Epilepsies, Partial;
Epilepsy;
Epilepsy, Generalized;
Epilepsy, Temporal Lobe*;
Humans;
Incidence;
Seizures, Febrile*;
Temporal Lobe*
- From:Journal of the Korean Neurological Association
2000;18(4):409-413
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Although a history of febrile convulsion (FC) is common in epilepsy patients, the preferential associa-tion of febrile convulsion with temporal lobe epilepsy (TLE) is not clear. METHODS:We obtained the FC data from "Paik and Bongsang hospital" epilepsy clinic. We classified epilepsy syndromes into generalized epilepsy (GE), temporal lobe epilepsy (TLE), extratemporal epilepsy (ETLE), unclassified partial and undetermined epilepsy by standardized criteria. The incidence of antecedent FC was evaluated in relation to the epilepsy classifications. We calculated kappa values for inter and intra observer reliability for the classifications of epilepsy syndromes. RESULTS: The agreement of epilepsy classifications were reliable (intra-observer kappa value=0.78, inter-observer kappa value=0.77). Thirteen percent of the studied patients (72/537) had a history of FC and 38% of FC (27/72) were complex types of FC. TLE was more likely to be preceded by FC 25% (42/166) than ETLE 6% (12/189), p<0.05 or GE 13% (12/93), p<0.05 and 85% of complex FC (23/27) preceded TLE. GE however, was more likely to have non-complex FC 100% (12/12) than partial epilepsy 55% (32/58), p<0.05. CONCLUSIONS We therefore conclude and agree that FC should be preferentially associated with TLE.
