A Case of Miller Fisher Syndrome Presenting as Sudden Vertigo.
- Author:
Sam Nam HONG
1
;
Ja Seong KOO
;
Byung Kun KIM
;
Sug Il KIM
;
Duck Min CHANG
;
Hee Joon BAE
Author Information
1. Department of Neurology, Eulji General Hospital, Eulji University School of Medicine.
- Publication Type:Case Report
- Keywords:
Miller fisher syndrome;
Vertigo;
Brainstem
- MeSH:
Ataxia;
Brain Stem;
Central Nervous System;
Cerebellar Ataxia;
Dizziness;
Female;
Humans;
Immunoglobulins;
Middle Aged;
Miller Fisher Syndrome*;
Ophthalmoplegia;
Quadriplegia;
Research Personnel;
Ventilators, Mechanical;
Vertigo*;
Walking
- From:Journal of the Korean Neurological Association
2000;18(4):486-489
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Ophthalmoplegia, ataxia, and areflexia are a classical triad of Miller Fisher syndrome (MFS). The experience of dizziness secondary to ophthalmoplegia is also not uncommon. However, nystagmus is rare and vertigo, a symptom of vestibulocerebellar dysfunction, has not been reported yet. A 56-year-old woman visited our hospital due to sudden vertigo. Initial examination revealed nystagmus evoked by a bilateral horizontal gaze with left side dysmetria. The next day, her symptoms rapidly aggravated to ophthalmoplegia, severe ataxia, areflexia, and quadriplegia. She was diag-nosed with MFS and was treated with intravenous immunoglobulin. On the fourth day, she developed respiratory fail-ure and a ventilator was applied. Twenty-eight days after her admission, she recovered to the point of walking without any aid and was discharged with minimal disability. There are still controversies surrounding the nosology of MFS and many investigators have reported evidence for brainstem involvement. Vertigo can be additional evidence for the involvement of the central nervous system in MFS.
