Delayed recovery of neuromuscular blockade by rocuronium in a hypothermic patient during a laparoscopic procedure: A case report.
10.4097/kjae.2009.56.2.195
- Author:
Ji Keun RYU
1
;
Byung Jun LEE
;
Kyung A YANG
;
Ouk JUNG
Author Information
1. Department of Anesthesiology and Pain Medicine, Dongkang Hospital, Ulsan, Korea. bowfamily@naver.com
- Publication Type:Case Report
- Keywords:
Hypothermia;
Laparoscopy;
Rocuronium
- MeSH:
Androstanols;
Humans;
Hypothermia;
Laparoscopy;
Neuromuscular Blockade;
Neuromuscular Blocking Agents;
Plasma;
Ventilators, Mechanical;
Viscera
- From:Korean Journal of Anesthesiology
2009;56(2):195-199
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Perioperative hypothermia can occur frequently and lead to various complications. Laparoscopic procedures do not require a large incision or exposure of the viscera, but a prolonged and high pressure procedure can lead to unexpected hypothermia. Hypothermia prolongs the time-course of non-depolarizing neuromuscular blocking agents by reducing the plasma clearance significantly. Rocuronium, a new aminosteroidal neuromuscular blocking agent, can be influenced by reductions in plasma clearance and prolong the duration of action. Therefore, patients must receive ventilator care in the ICU. Aggressive measures were taken for hypothermia, and the patient was discharged without any complications. We report a case of delayed of neuromuscular blockade by rocuronium in a hypothermic patient during a laparoscopic procedure with a brief review of literatures.
