Metallo-beta-lactamase Producing Gram-negative Bacilli.
10.5145/KJCM.2009.12.3.103
- Author:
Dongeun YONG
1
Author Information
1. Department of Laboratory Medicine and Research Institute of Bacterial Resistance, Yonsei University College of Medicine, Seoul, Korea. deyong@yuhs.ac
- Publication Type:Review
- Keywords:
Metallo-beta-lactamase;
Gram-negative bacilli
- MeSH:
Anti-Bacterial Agents;
beta-Lactams;
Drug Resistance, Microbial;
Gram-Negative Bacteria;
Gram-Negative Bacterial Infections;
Health Resorts;
Humans;
Korea
- From:Korean Journal of Clinical Microbiology
2009;12(3):103-109
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Among gram-negative bacteria, rate of antibiotic resistance has been increasing. As a result, carbapenem is now considered as a last resort of therapeutic regimens for gram-negative bacterial infections. The choice of antibiotics has been impeded by the spread of organisms producing metallo-beta-lactamases (MBL), which can confer resistance to nearly all beta-lactams. MBLs have extremely diverse structures and are carried by various organisms including human pathogens. This review will focus on the classification and current status of MBL reported in Korea.
