Ulcerative Necrobiosis Lipoidica Improved by Hydroxychloroquine.
- Author:
Hyun Ho SON
1
;
Tae Gwang KWON
;
Hyun Soo SIM
;
Sook Kyung LEE
Author Information
1. Department of Dermatology, Maryknoll Medical Center, Busan, Korea. sea7th@naver.com
- Publication Type:Case Report
- Keywords:
Hydrochloroquine;
Ulcerative necrobiosis lipoidica
- MeSH:
Bacterial Infections;
Cicatrix;
Diabetes Mellitus;
Humans;
Hydroxychloroquine;
Necrobiosis Lipoidica;
Necrobiotic Disorders;
Skin;
Skin Diseases;
Ulcer;
Young Adult
- From:Korean Journal of Dermatology
2012;50(11):994-997
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Necrobiosis lipoidica (NL) is a chronic granulomatous skin disease of unknown etiology, which can be seen in patients with diabetes mellitus. Typical lesions of NL appear on the pretibial skin as painful yellow-brown inflammatory plaques with raised borders and atrophic centers. Ulceration occurs in approximately 35% of cases, leading to increased risk of secondary bacterial infection and scarring. Although there have been many proposed therapies for ulcerative NL, the response to treatment is often met with limited success. Here, we report a case of a 19-year-old girl with ulcerative NL, which showed improvements with oral hydroxychloroquine, an antimalarial agent.
