Leukocytoclastic Vasculitis Associated with Influenza A Virus Infection.
10.3346/jkms.2012.27.12.1601
- Author:
Hyo Jin LEE
1
;
Dong Hoon SHIN
;
Jong Soo CHOI
;
Ki Hong KIM
Author Information
1. Department of Dermatology, Yeungnam University College of Medicine, Daegu, Korea. dhshin@med.yu.ac.kr
- Publication Type:Case Reports
- Keywords:
Leukocytoclastic Vasculitis;
Influenza A Virus Infection
- MeSH:
Anti-Inflammatory Agents/therapeutic use;
Antiviral Agents/therapeutic use;
Child, Preschool;
Female;
Fever/etiology;
Humans;
Influenza A virus/*genetics/isolation & purification;
Influenza, Human/*complications/drug therapy/virology;
Nasopharynx/virology;
Oseltamivir/therapeutic use;
Prednisolone/therapeutic use;
Reverse Transcriptase Polymerase Chain Reaction;
Skin/pathology;
Vasculitis, Leukocytoclastic, Cutaneous/*diagnosis/drug therapy/etiology
- From:Journal of Korean Medical Science
2012;27(12):1601-1603
- CountryRepublic of Korea
- Language:English
-
Abstract:
Leukocytoclastic vasculitis (LCV) usually presents palpable purpura characterized by inflammation of vessel walls and fragmentation of nuclei. Various conditions can cause LCV, and it can be induced by influenza A virus infection. We report a 2-yr-old Korean girl who presented palpable purpuric and hemorrhagic lesions with fever. She was diagnosed as LCV by skin biopsy, and influenza A virus was isolated from nasopharyngeal swab. She was treated with oseltamivir (Tamiflu(R)) and prednisolone with dramatic effect of vasculitis and fever.
