Clinical Characteristics and Survival of Elderly Patient with Klebsiella pneumoniae Bacteremia in Emergency Room.
10.4235/jkgs.2012.16.4.192
- Author:
Eun Ah HAN
1
;
Hyun Jong KIM
;
Sung Phil CHUNG
;
Kyung Min KIM
;
Chang Oh KIM
Author Information
1. Department of Emergency Medicine, Yonsei University College of Medicine, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Klebsiella pneumoniae;
Elderly;
Survival;
Bacteremia;
Emergency
- MeSH:
Aged;
Arterial Pressure;
Bacteremia;
Blood Urea Nitrogen;
Body Temperature;
Comorbidity;
Emergencies;
Humans;
Intensive Care Units;
Klebsiella;
Klebsiella pneumoniae;
Lactic Acid;
Logistic Models;
Medical Records;
Pneumonia;
Retrospective Studies;
Risk Factors;
Serum Albumin;
Survivors;
Tertiary Care Centers
- From:Journal of the Korean Geriatrics Society
2012;16(4):192-199
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Recently, the number of elderly patients with bacteremia has been increasing in the emergency room. Klebsiella pneumoniae is the second common agent of all gram negative bacteremia. We designed this study in order to describe the clinical characteristics and outcomes of elderly patients with K. pneumoniae bacteremia in the emergency room. METHODS: We retrospectively reviewed medical records of 109 patients infected with K. pneumoniae, who visited an emergency room of a tertiary hospital from March 2006 to October 2010. All patients were divided into two groups (83 survivors versus 26 nonsurvivors). We compared the outcomes and the clinical characteristics between the two groups. RESULTS: A total of 26 patients (23.9%) died in this study. There were no significant differences in age, sex, previous medical and surgical history between survivor and nonsurvivor groups. In the univariate logistic regression analysis, the significant favorable factors for survival associated with K. pneumoniae bacteremia were malignancy (odds ratio [OR], 0.311; p=0.018), Charlson comorbidity index (OR, 0.787; p=0.010), intensive care unit admission (OR, 0.260; p=0.032), mean arterial pressure (OR, 1.053; p=0.001), body temperature (OR, 2.250; p=0.001), blood urea nitrogen (OR, 0.969; p=0.002), albumin (OR, 6.739; p<0.001) and lactate (OR, 0.876; p=0.046). In a multiple logistic regression, the significant risk factors for predicting mortality were low body temperature (OR, 1.036; p=0.044) and low serum albumin (OR, 5.636; p=0.002) at the time of admission. CONCLUSION: Initial albumin level and body temperature were significant risk factors of mortality in elderly patients in the emergency room infected by K. pneumoniae bacteremia. Elderly patients with K. pneumoniae bacteremia in the emergency room should be carefully observed due to the high mortality rate.
