The Association between White Blood Cell Counts and Clustered Features of the Metabolic Syndrome.
- Author:
Tae Soon CHOI
1
;
Yoo Sun MOON
;
Young Ho CHOI
;
Seok Yun KO
;
Kyung Sub KWAK
;
Yun Ki KIM
Author Information
1. Department of Family Medicine, Chunchon Sacred Heart Hospital, Hallym College of Medicine, Korea. yoosmoo@hallym.ac.kr
- Publication Type:Original Article
- Keywords:
metabolic syndrome;
WBC counts;
clustering
- MeSH:
Adult;
Alcohol Drinking;
Blood Glucose;
Cholesterol, HDL;
Cluster Analysis;
Fasting;
Female;
Hematologic Tests;
Humans;
Hypercholesterolemia;
Hypertension;
Hypertriglyceridemia;
Hyperuricemia;
Leukocyte Count*;
Logistic Models;
Obesity;
Risk Factors;
Smoke;
Smoking
- From:Journal of the Korean Academy of Family Medicine
2004;25(1):34-39
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Increased WBC counts have been associated with different components of metabolic syndrome (MS), accompanied by clustering of a number of risk factors for CHD. Because most individuals have one or more of the risk factors for CHD or a cluster of MS symptoms, it may not be appropriate to look only at isolated components. Therefore, the aim of the present study was to examine the association of WBC counts with clustered features of MS in Korean adults. METHODS: The subject of this study included 593 adults (males 344, females 249) aged 20 years or older. Among the subjects, we excluded those who did not have records of physical parameters and blood test results and those who did not complete the questionnaire. We also excluded acutely ill patients. Logistic regression analyses were used to evaluate the association between WBC counts and features of the MS, with an adjustment for age, smoking and alcohol consumption. RESULTS: The relative risks for obesity, hypertension, hypercholesterolemia, low HDL cholesterol levels, hypertriglyceridemia, high fasting plasma glucose levels and hyperuricemia compared with WBC counts <5.2 x 10(3) cells/microliter, increased as WBC counts increased. The relative risks for the presence of > or =1, > or = 2, > or = 3, > or = 4 features of the MS also increased as WBC counts increased. CONCLUSION: An increased, albeit normal, WBC counts associates with the cluster of MS of the so-called "insulin resistance syndrome" and suggest that an increased WBC counts may be yet another feature of this syndrome.
