Gabapentin-induced Myoclonus in a Patient with End-stage Renal Disease.
- Author:
Seok Won HAN
1
;
Soo Yeon KIM
;
Min Kyung CHU
;
Kyung Ho YU
;
Yun Joong KIM
;
Byung Chul LEE
;
Jooyong KIM
Author Information
1. Department of Neurology, Hallym University College of Medicine, Anyang, Korea. joooyon@hotmail.com
- Publication Type:Case Report
- Keywords:
Gabapentin;
Myoclonus;
End-stage renal disease
- MeSH:
Brain;
Epilepsy;
Extremities;
Female;
Humans;
Kidney Failure, Chronic*;
Middle Aged;
Myoclonus*;
Paresthesia
- From:Journal of the Korean Neurological Association
2006;24(5):495-497
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Myoclonus manifests in a variety of situations including epilepsy, metabolic derangements, brain lesions, and toxicity of drugs. A 57-year-old woman with end-stage renal disease was given gabapentin 900 mg/day for legs' paresthesia. Two days after taking gabapentin, multifocal myoclonus developed involving all extremities. Three days after discontinuation of gabapentin, myoclonus resolved completely. No deterioration of renal function was noted before and after the occurrence of myoclonus. Administration of gabapentin should be performed with caution in patients with impaired renal function.
