A Study of Changes in Plasma Norepinephrine and Epinephrine to Halothane.
10.4097/kjae.1990.23.4.563
- Author:
Chong Sung KIM
1
;
In Cheol CHOI
;
Kwang Woo KIM
Author Information
1. Department of Anesthesiology, College of Mediciene, Seoul National University, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Halothane;
Anesthesia;
Norepinephrine;
Epinephrine
- MeSH:
Adult;
Anesthesia;
Animals;
Blood Pressure;
Epinephrine*;
Halothane*;
Heart Rate;
Humans;
Norepinephrine*;
Plasma*
- From:Korean Journal of Anesthesiology
1990;23(4):563-567
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The reaction to stress, while vital to the conscious animal, may be detrimental to the surgical patient. To assess the stress-associated action of halothane and its doses, we studied the responses in plasma norepinephrine, epinephrine, blood pressure and heart rate to changes of halothane concentration from 0 MAC to 1.5 MAC in 8 healthy adults. Systolic blood pressure, diastolic blood pressure and mean blood pressure were decreased as the concentration of the halothane increased from 0 MAC 0.5 MAC, 1.0 MAC and 1.5 MAC, respectively. But norepinephrine and epinephrine show no statistic ally significant response to changes in the concentration of halothane.
