Intra-arterial Blood Pressure Changes in Very Low Birth Weight Infants During the First Seven Days of Life.
- Author:
Young Jun KIM
1
;
Youn Hee JEE
;
Chae Hyeok LEE
;
Jung Are KIM
;
Young Pyo CHANG
Author Information
1. Department of Pediatrics, College of Medicine, Dankook University, Cheonan, Korea.
- Publication Type:Original Article
- Keywords:
Blood pressure;
Very low birth weight infant
- MeSH:
Birth Weight;
Blood Pressure*;
Critical Period (Psychology);
Gestational Age;
Hemorrhage;
Humans;
Infant*;
Infant, Newborn;
Infant, Very Low Birth Weight*;
Intensive Care, Neonatal;
Retrospective Studies
- From:Journal of the Korean Society of Neonatology
2001;8(1):110-118
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: We aimed to assess the influence of perinatal factors on intra-arterial mean blood pressures of very low birth weight infants during the first seven days of life and the association of intra-arterial mean blood pressures on the common morbidities and neonatal death of very low birth weight infants. METHODS: The retrospective study on intra-arterial mean blood pressures over the first seven days of life in 103 very low birth weight infants who admitted to the neonatal intensive care unit at the Dankook University Hospital from Jan. 1996 to Dec. 2000 was done. Trend data for each infants were assessed in 9 time periods until seven days of age. Perinatal factors that might influence intra-arterial mean blood pressures and the association of intra-arterial mean blood pressures on neonatal death and common morbidities were assessed. RESULTS: Intra-arterial mean blood pressures of very low birth weight infants increased with birth weight and gestational age (P<0.05), and significantly increased with postnatal age over the seven day periods from 35.0+/-4.9 mmHg (period 1) to 44.2+/-6.5 mmHg (period 9). Intra-arterial mean blood pressures of infants weighing less than 1,000 g were significantly lower than infants weighing 1,000 to 1,499 g at all each time periods (P< 0.05). Intra-arterial mean blood pressures were found to correlate significantly with antenatal steroid (P<0.005), and correlate inversely with PDA (P<0.001), pulmonary hemorrhage (P<0.005) and ROP (P<0.05). CONCLUSION: Intra-arterial mean blood pressures in very low birth weight infants during the first seven days were found to correlate significantly with postnatal age, gestational age, birth weight and antenatal steroid and probably correlate with some common morbidities of very low birth weight infants. It is therefore important to maintain adequate blood pressure ranges during the first seven days of life that are the most critical periods of illness for the majority of very low birth weight infants.
