A Case of Koebner Variant of Epidermolysis Bullosa Simplex.
- Author:
Seong Joon LIM
1
;
Soon Pil JUNG
;
In Seok LIM
;
Dong Keun LEE
;
Byung Hoon YOO
Author Information
1. Department of Pediatrics, College of Medicine, Chungang University, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Epidermolysis bullosa simplex;
Koebner variant;
Neonate
- MeSH:
Blister;
Epidermolysis Bullosa Simplex*;
Epidermolysis Bullosa*;
Fathers;
Friction;
Humans;
Infant, Newborn;
Keratin-5;
Keratinocytes;
Male;
Seasons
- From:Journal of the Korean Society of Neonatology
2001;8(1):166-170
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Epidermolysis bullosa simplex (EBS), characterized by a cleavage plane through basal keratinocytes, is caused by a mutation of the genes encoding keratin 5 and 14. It is often regarded as the least severe form of Epidermolysis bullosa. In 1886, Koebner described the seasonal blisterings predominantly on the palms and soles but occurring on the other sites of friction with clothes as well. His name is often used to describe EBS with the generalized blisterings. We have experienced a case of Koebner variant of EBS in a two-day old male neonate whose father had the same EBS. Hereby, we report his clinical, histopathological findings with a brief review of the literature.
