A Case of Diphyllobothrium nihonkaiense Infection as Confirmed by Mitochondrial COX1 Gene Sequence Analysis.
10.3347/kjp.2013.51.4.471
- Author:
Sang Hyun PARK
1
;
Keeseon S EOM
;
Min Sun PARK
;
Oh Kyoung KWON
;
Hyo Sun KIM
;
Jai Hoon YOON
Author Information
1. Department of Internal Medicine, Chuncheon Sacred Heart Hospital, Chuncheon 200-704, Korea. yoonjh@hallym.or.kr
- Publication Type:Case Reports
- Keywords:
Diphyllobothrium nihonkaiense;
Diphyllobothrium latum;
DNA;
sequence;
cox1;
diagnosis
- MeSH:
Animals;
Cyclooxygenase 1/*genetics;
Diphyllobothriasis/*parasitology;
Diphyllobothrium/enzymology/genetics/*isolation & purification;
Female;
Helminth Proteins/*genetics;
Humans;
Mitochondrial Proteins/*genetics
- From:The Korean Journal of Parasitology
2013;51(4):471-473
- CountryRepublic of Korea
- Language:English
-
Abstract:
Diphyllobothrium nihonkaiense has been reported in Korea as Diphyllobothrium latum because of their close morphologic resemblance. We have identified a human case of D. nihonkaiense infection using the mitochondrial cytochrome c oxidase subunit I (cox1) gene sequence analysis. On 18 February 2012, a patient who had consumed raw fish a month earlier visited our outpatient clinic with a long tapeworm parasite excreted in the feces. The body of the segmented worm was 2 m long and divided into the scolex (head) and proglottids. It was morphologically close to D. nihonkaiense and D. latum. The cox1 gene analysis showed 99.4% (340/342 bp) homology with D. nihonkaiense but only 91.8% (314/342 bp) homology with D. latum. The present study suggested that the Diphyllobothrium spp. infection in Korea should be analyzed with specific DNA sequence for an accurate species identification.
