Two Cases of Deep Vein Thrombosis Associated with Behcet's Disease.
- Author:
Hong Suk KIM
1
;
Sung Nam CHANG
;
Eun Sun CHOI
;
Doyeun OH
;
Wook Hwa PARK
Author Information
1. Department of Dermatology, College of Medicine Pochon CHA University, Pundang CHA Hospital, Pundang.
- Publication Type:Case Report
- Keywords:
Behcet's disease;
Deep vein thrombosis;
Protein C and S
- MeSH:
Humans;
Leg;
Protein C;
Protein S Deficiency;
Thrombosis;
Venous Thrombosis*
- From:Korean Journal of Dermatology
2000;38(1):95-98
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
In Behcet's disease(BD), there is a marked increase in vascular complication. Venous thrombosis is a major feature of the disease, although arterial thrombosis is rarely described. In Behcet's disease, thrombosis occurs in 20 to 30% of patients. We present two cases of Behcet's disease admitted to our hospital whose chief complaint was progressive increases in swelling and pain in their legs. In the first case, routine coagulation tests and sero-immunological tests were within normal limits, however, protein C and S activity were significantly decreased in the patient. So these findings suggest that auto-immune acquired protein S deficiency may be involved in the pathogenesis of thrombotic events in BD.
