Visceral Leishmaniasis Mimicking Autoimmune Hepatitis, Primary Biliary Cirrhosis, and Systemic Lupus Erythematosus Overlap.
10.3347/kjp.2012.50.2.133
- Author:
Ozlem Guzel TUNCCAN
1
;
Abdurrahman TUFAN
;
Gulcin TELLI
;
Nalan AKYUREK
;
Merve PAMUKCUOGLU
;
Guldal YILMAZ
;
Kenan HIZEL
Author Information
1. Department of Clinical Microbiology and Infectious Diseases, Gazi University Hospital Besevler, 06500, Ankara, Turkey. oguzel@gazi.edu.tr
- Publication Type:Case Reports
- Keywords:
Leishmania;
visceral leishmaniasis;
systemic lupus erythematosus;
autoimmune hepatitis;
primary biliary cirrhosis
- MeSH:
Adult;
Autoantibodies/blood;
Bone Marrow/pathology;
Cytological Techniques;
Diagnosis, Differential;
Female;
Hepatitis, Autoimmune/complications/*pathology;
Histocytochemistry;
Humans;
Leishmaniasis, Visceral/complications/*diagnosis/*pathology;
Liver/pathology;
Liver Cirrhosis, Biliary/complications/*pathology;
Lupus Erythematosus, Systemic/complications/*pathology
- From:The Korean Journal of Parasitology
2012;50(2):133-136
- CountryRepublic of Korea
- Language:English
-
Abstract:
Visceral leishmaniasis (VL) is a life-threatening infection caused by Leishmania species. In addition to typical clinical findings as fever, hepatosplenomegaly, and cachexia, VL is associated with autoimmune phenomena. To date, VL mimicking or exacerbating various autoimmune diseases have been described, including systemic lupus erythematosus (SLE), rheumatoid arthritis, and autoimmune hepatitis (AIH). Herein, we presented a patient with VL who had overlapping clinical features with SLE, AIH, as well as antimitochondrial antibody (AMA-M2) positive primary biliary cirrhosis.
