Prevalence of Spirometrically-defined Restrictive Ventilatory Defect in Korea: The Fourth-2, 3, and Fifth Korean National Health and Nutrition Examination Survey, 2008-2012.
10.3346/jkms.2015.30.6.725
- Author:
Jung Yeon LEE
1
;
Yong Il HWANG
;
Yong Bum PARK
;
Jae Yong PARK
;
Ki Uk KIM
;
Yeon Mok OH
;
Hyoung Kyu YOON
;
Ho Il YOON
;
Sueng Su SHEEN
;
Sang Yeub LEE
;
Chang Hoon LEE
;
Heung Bum LEE
;
Sung Chul LIM
;
Sung Soo JUNG
;
Kyungwon OH
;
Yuna KIM
;
Chaemin CHUN
;
Kwang Ha YOO
Author Information
1. Department of Internal Medicine, Division of Pulmonary and Critical Care Medicine, Konkuk University Medical Center, Chungju Hospital, Chungju, Korea.
- Publication Type:Original Article
- Keywords:
Epidemiology;
Lung Diseases, Interstitial;
Respiratory Function Tests;
Tuberculosis;
X-Rays
- MeSH:
Adult;
Age Distribution;
Aged;
Aged, 80 and over;
Educational Status;
Female;
Health Care Surveys;
Housing;
Humans;
Income;
Lung Diseases, Obstructive/*diagnosis/*epidemiology;
Male;
Middle Aged;
Prevalence;
Reproducibility of Results;
Republic of Korea/epidemiology;
Risk Factors;
Sensitivity and Specificity;
Sex Distribution;
Smoking/*epidemiology;
Spirometry/*statistics & numerical data
- From:Journal of Korean Medical Science
2015;30(6):725-732
- CountryRepublic of Korea
- Language:English
-
Abstract:
The aim of the study was to evaluate the prevalence of restrictive ventilatory defect and to determine the risk factors in subjects with spirometrically-defined restrictive ventilatory defect. We used the population-based, fourth-2, 3 (2008, 2009) and fifth (2010-2012) Korea National Health and Nutrition Examination Survey (KNHANES) to analyze 15,073 subjects, aged > or =40 yr who underwent spirometry. Chest radiographs were also analyzed to identify restrictive lung disease. Spirometrically-defined restrictive ventilatory defect (FEV1/FVC> or =70% and FVC<80% of mean predicted value) was detected in 11.3% (n= 1,709) of subjects aged > or =40 yr. The prevalence increased to 12.3% on using the lower limit of normal (LLN) criteria. Approximately 99.4% of subjects were classified as mild restrictive. Among these, 11.3% had inactive tuberculosis (TB) lesion, 2.2% cardiac disease, 2.0% previous operation scar or radiation injury and/or mediastinal disease, and 7.4% other pulmonary disease suggestive of restrictive lung diseases on chest radiograph. Evidence of previous TB history was independently associated with restrictive ventilatory defect (odds ratios [OR], 1.78; 95% confidence interval, 1.45-2.18) after adjustment for gender, age, smoking, area for residence and body mass index. The prevalence of restrictive ventilatory defect among the nationwide population in Korea was 11.3% with fixed ratio criterion and 12.3% with LLN criterion. Most cases were of the mild restrictive category and previous TB history is the independent risk factor for restrictive ventilatory defect.
