Single Center Experience of Five Diffuse Panbronchiolitis Patients Clinically Presenting as Severe Asthma.
10.3346/jkms.2015.30.6.823
- Author:
Kyung Hee PARK
1
;
Hye Jung PARK
;
Jae Hyun LEE
;
Jung Won PARK
Author Information
1. Department of Internal Medicine and Institute of Allergy, Yonsei University College of Medicine, Seoul, Korea. parkjw@yuhs.ac
- Publication Type:Case Reports
- Keywords:
Diffuse Panbronchiolitis;
Asthma;
Clarithromycin
- MeSH:
Adult;
Aged;
Anti-Asthmatic Agents/*therapeutic use;
Asthma/*diagnosis/*drug therapy;
Bronchiolitis/*diagnosis/*drug therapy;
Diagnosis, Differential;
Female;
Haemophilus Infections/*diagnosis/*drug therapy;
Humans;
Macrolides/*administration & dosage;
Male;
Middle Aged;
Severity of Illness Index;
Treatment Outcome
- From:Journal of Korean Medical Science
2015;30(6):823-828
- CountryRepublic of Korea
- Language:English
-
Abstract:
Diffuse panbronchiolitis (DPB) is a bronchiolitis affecting the whole lung fields which can be treated by macrolide. Especially East Asian patients are more susceptible to diffuse panbronchiolitis. As asthma and DPB both can cause airway obstruction, differential diagnosis is important for the 2 diseases. Here we report 5 patients with DPB clinically presenting as severe asthma in Korea, who were well treated by macrolide. Among the 5 patients, 2 could stop their asthma inhalers and the other 3 could reduce asthma medications after diagnosis and treatment of DPB. In conclusion, considering DPB as differential diagnosis for asthmatics in Asian ethnic groups is important.
