Pulmonary Fungal Ball of Pseudallescheria boydiiIdentified by LSU rDNA D2 Region Sequencing.
10.5145/KJCM.2009.12.2.87
- Author:
Miyoung KIM
1
;
Mi Hee AHN
;
Ji Sang KANG
;
Hyun LEE
;
Sei Ick JOO
;
Sung Sup PARK
;
Eui Chong KIM
Author Information
1. Department of Laboratory Medicine, Seoul National University Hospital, Seoul, Korea. euichong@snu.ac.kr
- Publication Type:Case Report
- Keywords:
Scedosporium apiospermum;
Pseudallescheria boydii;
Pseudallescheria ellipsoidea
- MeSH:
DNA, Ribosomal;
Female;
Hemoptysis;
Humans;
Itraconazole;
Middle Aged;
Pseudallescheria;
Scedosporium
- From:Korean Journal of Clinical Microbiology
2009;12(2):87-91
- CountryRepublic of Korea
- Language:English
-
Abstract:
We report a case of pulmonary fungal ball of Pseudallescheria boydii (Scedosporium apiospermum, the anamorph) and the result of LSU rDNA D2 region sequencing of the clinical isolate. An immunocompetent 58-year-old female suffered 2-year history of hemoptysis. Her symptom persisted despite the administration of oral itraconazole, even though the clinical, radiological, and histological findings suggested Aspergilloma. In the fungal culture, the typical morphology of S. apiospermum was observed. Even though the sequencing using LSU rDNA D2 region identified the organism as Pseudallescheria ellipsoidea, one of the P. boydii complex, the further investigation of ours suggested that the species in P. boydii complex could not be differentiated from each other by the sequencing of LSU rDNA D2 region.
