The Usefulness of Birth Weight Z-Score as a Predictor of Catch Up Growth in Preterm Infants.
- Author:
Huee Jin PARK
1
;
Hae Yun LEE
;
Hae Kyung WOO
;
Seon Nyo KIM
;
Juyoung LEE
;
Hye Ran YANG
;
Beyong Il KIM
;
Chang Won CHOI
Author Information
- Publication Type:Original Article
- Keywords: Small for gestational age; Preterm; Catch up growth; Z-score; High calorie nutritional support
- MeSH: Birth Weight*; Cohort Studies; Gastroenterology; Gestational Age; Humans; Infant; Infant, Newborn; Infant, Premature*; Logistic Models; Nutritional Support; Parturition*; Retrospective Studies; Risk Factors; Triglycerides; Weight Gain
- From:Neonatal Medicine 2015;22(3):142-149
- CountryRepublic of Korea
- Language:Korean
- Abstract: PURPOSE: The aim of the study was to examine whether the degree of fetal smallness in small for gestational age (SGA) infants would increase the risk of catch-up-growth failure at 12 and 24 months corrected age (CA), and whether the high-calorie nutritional support would improve catch-up growth between 12 and 24 months CA. METHODS: We conducted a retrospective cohort study on 103 preterm infants born between January 2010 and December 2011. Logistic regression analysis was performed to investigate whether the birth weight z-score would be an independent risk factor for catch-up growth failure at 12 or 24 months CA. Among the 46 infants with failed catch-up growth at 12 months CA, 16 infants were provided high-calorie nutritional support, including nutritional supplements and medium chain triglyceride (MCT) oil at the pediatric gastroenterology clinic. RESULTS: Of 103 preterm infants, 34 infants (33%) were SGA and 69 infants (67%) were appropriate for gestational age (AGA). One birth weight z-score decrement increased the odds for catch-up growth failure 2.9 times at 12 months CA and 3.0 times at 24 months CA after adjustment for major neonatal morbidities. The increase in z-score between 12 and 24 months CA was significantly greater in the infants provided nutritional support than in the infants who were not provided nutritional support. CONCLUSION: The birth weight z-score can be used as a predictor of catch-up growth failure. High-calorie nutritional support may improve weight gain during the second year in preterm infants with failed catch-up growth at 12 months CA.
