Effect of Dorzolamide on Corneal Endothelium.
- Author:
In Ki PARK
1
;
Ji Young KIM
;
Won Ryang WEE
;
Dong Myung KIM
Author Information
1. Department of Ophthalmology, College of Medicine, Seoul National University.
- Publication Type:Original Article
- Keywords:
Corneal endothelial permeability;
Corneal thickness;
Dorzolamide
- MeSH:
Carbonic Anhydrases;
Endothelial Cells;
Endothelium, Corneal*;
Intraocular Pressure;
Permeability
- From:Journal of the Korean Ophthalmological Society
1999;40(4):915-920
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The purpose of this study was to investigate the effect of 2% dorzolamide, a topical carbonic anhydrase inhibitor, on corneal endothelium. Corneal endothelial permeability, central corneal thickness, central corneal endothelial cell density and intraocular pressure were measured in both eyes before(baseline) and after the use of 2% dorzolamide t.i.d. in one eye for one week. There was significant decrease in intraocular pressure(p=0.04) after the use of 2% dorzolamide t.i.d. for one week, but there were no significant changes in corneal endothelial permeability, central corneal thickness and central corneal endothelial cell density(p>0.05 in all).
