Amiodarone Induced Keratopathy.
- Author:
Jun Ho HEO
1
;
Ji Young KIM
;
Chul Ho KIM
Author Information
1. Department of Ophthalmology, Seoul Municipal Boramae Hospital.
- Publication Type:Original Article
- Keywords:
Amiodarone;
Amiodarone keratopathy;
Amiodarone toxicity
- MeSH:
Action Potentials;
Amiodarone*;
Arrhythmias, Cardiac;
Humans;
Retrospective Studies
- From:Journal of the Korean Ophthalmological Society
1999;40(4):921-925
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Amidarone hydrochloride, benzofuran derivatives, particularly effective for the treatment of arrythmias by prolong the duration of the action potential in all cardiac-conducting tissues. We studied the 25 patients with typical amiodarone keratopathy, retrospectively. In 25 patients, ten patients developed grade 1, eleven patients developed grade 2, and four patients developed grade 3 keratopathy. They complained of decreased best corrected visual acuity(1 patient), halos(1 patient), hypothyroidism(3 patients), pulmonary toxicity(2 patients), thpatic dysfunction(5 patients) and sleep dusturbance(3 patients). Therefore ophthalmologists should be alert for the complications of amiodarone and regular careful slit-lamp examination will be helpful in minimizing amidarone toxicity.
