Cloudy urine developed during total intravenous anesthesia with 2% propofol in the patient taking hydroxyurea: A case report.
10.17085/apm.2017.12.3.230
- Author:
Boo young HWANG
1
;
Jae young KWON
;
Hae kyu KIM
;
Eunsoo KIM
;
Suyeon HONG
;
Jung min HONG
Author Information
1. Department of Anesthesia and Pain Medicine, Pusan National University Hospital, Busan, Korea. ccarrot@pusan.ac.kr
- Publication Type:Case Report
- Keywords:
Cloudy urine;
Hydroxyurea;
Propofol;
Uric acid
- MeSH:
Aged;
Anesthesia, Intravenous*;
Blood Urea Nitrogen;
Creatinine;
Humans;
Hydrogen-Ion Concentration;
Hydroxyurea*;
Kidney;
Operating Rooms;
Propofol*;
Thrombocythemia, Essential;
Uric Acid
- From:Anesthesia and Pain Medicine
2017;12(3):230-232
- CountryRepublic of Korea
- Language:English
-
Abstract:
We report a case that a 68-year-old man taking hydroxyurea for essential thrombocythemia produced milky urine during propofol infusion. Under microscopic analysis, the cloudy urine sample was revealed to comprise uric acid crystals. Postoperatively, kidney function such as urine output and blood urea nitrogen to creatinine ratio showed no abnormality. We suggest that the cloudy urine may be due to the increased excretion of uric acid after administration of propofol. Although this rare case of cloudy milky urine is resolved on its own, we need to consider the possibility of such urine color changes. It is particularly important to understand that medication, preoperative serum uric acid level, urine pH, and the hypothermal operating room can change the color of urine through the presence of uric acid crystals.
