A Case of Hodgkin`s Lymphoma with Bone Marrow Involvement Showing Severe Osteosclerosis.
- Author:
Sang Hoon SONG
1
;
Hye Seung LEE
;
Kyoung Un PARK
;
Junghan SONG
Author Information
1. Department of Laboratory Medicine, Seoul National University College of Medicine, Seoul, Korea. m91w95@dreamwiz.com
- Publication Type:Case Report
- Keywords:
Osteosclerosis;
Hodgkin`s lymphoma;
Bone marrow involvement
- MeSH:
Back Pain;
Biopsy;
Bone Marrow*;
Diagnosis;
Drug Therapy;
Eosinophilia;
Granuloma;
Humans;
Immunohistochemistry;
Lymphoma*;
Male;
Osteosclerosis*;
Prognosis
- From:The Korean Journal of Laboratory Medicine
2005;25(1):24-27
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Bone marrow involvement in Hodgkin`s lymphoma is not rare at initial diagnosis and is associated with a poor prognosis. Atypical findings such as granuloma, eosinophilia or osteosclerosis may lead to diagnostic confusion, in which case immunohistochemistry may be helpful. We report a case of 25-year old male patient, who presented with back pain, subsequently had a mediastinal mass and was finally diagnosed as having stage IV Hodgkin`s lymphoma. Bone marrow involvement with severe osteosclerosis was found on bone marrow biopsy specimens. He received systemic chemotherapy and was discharged with improved clinical symptoms.
