Effect of Topical Steroid (0.05% Clobetasol Propionate) Treatment in Children With Severe Phimosis.
10.4111/kju.2013.54.9.624
- Author:
Chan Ho LEE
1
;
Sang Don LEE
Author Information
1. Department of Urology, Pusan National University School of Medicine, Yangsan, Korea. lsd@pusan.ac.kr
- Publication Type:Original Article
- Keywords:
Circumcision;
Phimosis;
Steroids
- MeSH:
Child;
Circumcision, Male;
Clobetasol;
Foreskin;
Humans;
Male;
Massage;
Phimosis;
Retrospective Studies;
Skin;
Smegma;
Steroids;
Urinary Tract Infections
- From:Korean Journal of Urology
2013;54(9):624-630
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: We report our experience with the use of a topical steroid, 0.05% clobetasol propionate, for the treatment of phimosis with clinical complications. MATERIALS AND METHODS: This was a retrospective analysis of the clinical outcomes of all patients presenting with phimosis to a single institution during the time period from October 2008 to May 2012. A total of 88 patients who had a Kikiros retractability grade of 4 or 5 and phimosis-associated clinical complications, such as ballooning of the prepuce, balanoposthitis, or a history of urinary tract infection (UTI), were instructed to apply 0.05% clobetasol propionate cream to the slightly retracted foreskin and to massage gently while retracting the foreskin. The efficacy of treatment was evaluated at 4 weeks from the initiation of therapy. RESULTS: A total of 60 of the 88 patients (68.2%) showed a complete response (i.e., full retraction of the foreskin) to the therapy. The phimotic ring disappeared in 25 of the 88 patients (28.4%) after treatment. Patients who had a history of balanoposthitis, smegma, ballooning of the prepuce, or UTI showed significantly poorer improvement in preputial retraction (p<0.001, p<0.001, p<0.001, and p=0.02, respectively) and phimotic ring disappearance (p<0.001, p=0.001, p<0.001, and p=0.001, respectively) after treatment. No significant local or systemic side effects were associated with the administration of topical steroids. CONCLUSIONS: Topical application of 0.05% clobetasol propionate cream and skin stretching is a safe, simple, and effective procedure with no significant side effects for severe phimosis in prepubertal boys.
