Contrast-enhanced Magnetic Resonance Imaging of Brain Metastases at 7.0T versus 1.5T: A Preliminary Result.
10.13104/imri.2015.19.1.31
- Author:
Sun Ha PAEK
1
;
Jhi Hoon KIM
;
Sung Hong CHOI
;
Tae Jin YOON
;
Young Don SON
;
Dong Gyu KIM
;
Zang Hee CHO
;
Chul Ho SOHN
Author Information
1. Department of Neurosurgery, Seoul National University Hospital, Cancer Research Institute, Ischemic/Hypoxic Disease Institute, Seoul National University College of Medicine, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Brain metastasis;
Magnetic resonance imaging;
7T MRI
- MeSH:
Brain*;
Consensus;
Humans;
Magnetic Resonance Imaging*;
Meglumine;
Neoplasm Metastasis*
- From:Investigative Magnetic Resonance Imaging
2015;19(1):31-36
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: To compare the depiction of brain metastases on contrast-enhanced images with 7.0 tesla (T) and at 1.5T MRI. MATERIALS AND METHODS: Four consecutive patients with brain metastases were scanned on 7.0T whole-body scanner and 1.5T MRI. A 3D T1-weighted gradient echo sequence (3D T1-GRE) at 1.5T (voxel size = 0.9 x 0.9 x 1.5 mm3 after double-dose, gadoterate meglumine, Gd-DOTA) was compared to a 7.0T 3D T1-GRE sequence (voxel size = 0.4 x 0.4 x 0.8 mm3, single-dose Gd-DOTA) in four patients after a 5 minute delay. The number of contrast-enhancing metastases in MPRAGE images was compared in each patient by two radiologists in consensus. We measured contrast ratio of enhancing brain metastases and white matter in 1.5T and 7.0T. RESULTS: In all four patients 7.0T 3D T1-GRE images after single-dose Gd-DOTA and 1.5T after double-dose Gd-DOTA depicted 11 brain metastases equally. In the quantitative analysis of contrast ratios of enhancing brain metastases and white matter, the 1.5T 3D T1-GRE after double-dose showed an increased contrast ratio compared to 7.0T 3D T1-GRE after single-dose (0.961 +/- 0.571 versus 0.885 +/- 0.494; n = 11 metastases). But this difference was not statistically significant (P = 0.711). CONCLUSION: Our preliminary results indicate that 7.0T single-dose Gd-enhanced images were not different to 1.5T double-dose Gd-enhanced images for the detection of brain metastases.
