MR Imaging Findings of Tamoxifen-associated Uterine Adenosarcoma: Report of Two Cases.
10.13104/imri.2015.19.1.56
- Author:
Soo Yeon CHOI
1
;
Deuk Jae SUNG
;
Na Yeon HAN
;
Beom Jin PARK
;
Min Ju KIM
;
Ki Choon SIM
;
Sung Bum CHO
Author Information
1. Department of Radiology, Anam Hospital, College of Medicine, Korea University, Seoul, Korea. urorad@korea.ac.kr
- Publication Type:Case Report
- Keywords:
Magnetic resonance imaging;
Uterine adenosarcoma;
Estrogen receptor modulators;
Breast cancer
- MeSH:
Adenosarcoma*;
Breast Neoplasms;
Estrogen Receptor Modulators;
Humans;
Magnetic Resonance Imaging*;
Tamoxifen;
Toremifene;
Uterus;
Vagina
- From:Investigative Magnetic Resonance Imaging
2015;19(1):56-61
- CountryRepublic of Korea
- Language:English
-
Abstract:
Adenosarcoma of the uterus is a rare biphasic tumor containing benign glandular epithelial and malignant mesenchymal components. The tumor has been reported to be associated with antiestrogen therapy, particularly tamoxifen, but there have been a few case reports with MRI. We present two cases of MRI findings of uterine adenosarcoma after antiestrogen therapy, tamoxifen and toremifene in breast cancer patients. The tumor presents as a large polypoid mass occupying the endometrial cavity, and may protrude into the vagina. On MRI, the tumor typically shows solid components with scattered small cysts and heterogeneous enhancement. These findings are not significantly different from conventional adenosarcoma.
