Epstein-Barr virus associated posttransplant malignant lymphoma in renal allograft recipients.
10.3346/jkms.1994.9.2.162
- Author:
Yeong Jin CHOI
1
;
Chang Suk KANG
;
Wan Shik SHIN
;
Mi Kyoung JEE
;
Byoung Kee KIM
;
Sun Moo KIM
;
Sang In SHIM
Author Information
1. Department of Clinical Pathology, Catholic University Medical College, Seoul, Korea.
- Publication Type:Case Reports
- MeSH:
Adult;
Female;
*Herpesvirus 4, Human/isolation & purification;
Humans;
In Situ Hybridization;
Kidney Transplantation/*adverse effects/pathology;
Lymphoma/*complications/pathology/virology;
Male;
Middle Aged;
Transplantation, Homologous;
Tumor Virus Infections/*complications
- From:Journal of Korean Medical Science
1994;9(2):162-168
- CountryRepublic of Korea
- Language:English
-
Abstract:
We report two cases of posttransplant malignant lymphoma(PTML) of B cell origin associated with Epstein-Barr virus(EBV) infection. They were a 52-year-old male and a 37 year-old-female, in whom intermediate-grade diffuse malignant lymphomas of large cell type developed in the submandibular area and jejunum, respectively. DNA and RNA in situ hybridization revealed the presence of EBV-specific DNA and RNA sequences in the tumor cells.
