The Short Time Antibacterial Effect of Tetracaine Hydrochloride(Pontocaine(R)): in vitro study.
- Author:
Se Woong KANG
1
;
Jin Hak LEE
Author Information
1. Department of Ophthalmology, College of Medicine, Seoul National University, Seoul, Korea.
- Publication Type:In Vitro ; Original Article
- Keywords:
tetracaine hydrochloride;
antibacterial effect;
short time exposure
- MeSH:
Agar;
Coagulase;
Staphylococcus;
Tetracaine*
- From:Journal of the Korean Ophthalmological Society
1989;30(3):331-334
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The short time antibacterial effect of tetracaine hydrochloride was studied. S. aureus, Coagulase Negative Staphylococcus and P. aeruginosa were each incubated with tetracaine hydrochloride(preservative free) for 18 hours or for 2 minutes and then diluted and cultured on nutrient agar plate. Colony counts were done after 18 hours. In cases of 18 hours incubation, there was no growth of microbials in 0.5%, 0.1% tetracaine hydrochloride, but there was no inhibitory effect of 0.02% of tetracaine hydrochloride on growth of microbials, irrespective of inoculum amount. In cases of 2 minutes incubation with 0.5% tetracaine hydrochloride, there was no difference between the amount of microbial inoculum and colony count. Above in vitro study indicates that tetracaine hydrochloride has no inhibitory effect on bacterial growth in short time exposure less than 2 minutes.
