- Author:
Su Young CHI
1
;
Tae Ok KIM
;
Chan Woo PARK
;
Jin Yeong YU
;
Boram LEE
;
Ho Sung LEE
;
Yu Il KIM
;
Sung Chul LIM
;
Yong Soo KWON
Author Information
- Publication Type:Original Article
- Keywords: Pneumonia, Ventilator Associated; Staphylococcus aureus; Acinetobacter baumanii
- MeSH: Acinetobacter; Adult; Bronchoalveolar Lavage; Humans; Imipenem; Intensive Care Units; Klebsiella pneumoniae; Methicillin Resistance; Pneumonia, Ventilator-Associated; Pseudomonas aeruginosa; Referral and Consultation; Serratia marcescens; Staphylococcus aureus; Stenotrophomonas maltophilia; Tertiary Care Centers; Ventilators, Mechanical
- From:Tuberculosis and Respiratory Diseases 2012;73(1):32-37
- CountryRepublic of Korea
- Language:English
- Abstract: BACKGROUND: This study evaluates the bacterial pathogens of Ventilator-associated pneumonia (VAP) in a tertiary referral hospital. METHODS: A total of 109 bacterial pathogens from 91 adult patients with VAP, who were admitted to the medical intensive care unit from January 2008 to December 2009, were examined. Clinical characteristics, bacterial pathogens, and resistance profiles were analyzed. RESULTS: Staphylococcus aureus (44%) was the most frequently isolated. Acinetobacter baumanii (30%), Pseudomonas aeruginosa (12%), Stenotrophomonas maltophilia (7%), Klebsiella pneumoniae (6%), and Serratia marcescens (2%) were isolated from the transtracheal aspirates or bronchoalveolar lavage in patients with VAP. There was no significant difference of bacterial pathogens between early and late onset VAP. All isolated S. aureus were methicillin resistant S. aureus; the imipenem resistance rate of A. baumanii was 69%. CONCLUSION: The two most frequent pathogens of VAP were S. aureus and A. baumanii. There were no pathogenic differences between early and late onset VAP.