Cholestasis Causes Discrepancy in HDL-Cholesterol Levels Measured Using Various Methods.
- Author:
Sollip KIM
1
;
Sail CHUN
;
Woochang LEE
;
Ghi Su KIM
;
Won Ki MIN
Author Information
- Publication Type:Case Report
- Keywords: HDL-Cholesterol; Cholestasis; Discrepancy
- MeSH: Apolipoproteins; Cholestasis; Electrophoresis, Agar Gel; Lipoproteins
- From:Laboratory Medicine Online 2012;2(3):174-178
- CountryRepublic of Korea
- Language:Korean
- Abstract: Herein, we report a case in which cholestasis caused discrepancy in high-density lipoprotein (HDL)-cholesterol levels measured using various methods. The discrepancy in HDL-cholesterol level originated from the abnormal increase in the level of an unusual lipoprotein, apo E-rich HDL, in the patient's serum. An abnormal slow alpha-migrating lipoprotein was observed on agarose gel electrophoresis, and an abnormal large-sized HDL was observed in a lipoprotein subfraction study. The level of apolipoprotein E was elevated.
