Autoimmune Hemolytic Anemia after Aplastic Crisis due to Parvovirus B19 Infection in a Patient with Hereditary Spherocytosis.
- Author:
Sae Am SONG
1
;
Min Young LEE
;
Si Hyun KIM
;
Ja Young LEE
;
Seung Hwan OH
;
Jeong Hwan SHIN
;
Hye Ran KIM
;
Kyung Ran JUN
;
Jeong Nyeo LEE
Author Information
- Publication Type:Case Report
- Keywords: Hereditary spherocytosis; Parvovirus B19; Autoimmune hemolytic anemia
- MeSH: Anemia, Hemolytic; Anemia, Hemolytic, Autoimmune; Arthritis; Autoimmune Diseases; Cell Membrane; Child; Cytoskeletal Proteins; Erythema Infectiosum; Humans; Parvovirus; Spherocytes; Spherocytosis, Hereditary
- From:Laboratory Medicine Online 2012;2(3):166-169
- CountryRepublic of Korea
- Language:Korean
- Abstract: Hereditary spherocytosis (HS) is a genetic disorder characterized by the production and destruction of spherocytes due to a deficiency of red cell membrane cytoskeletal proteins, resulting in the clinical presentation of chronic hemolytic anemia. This disease can be accompanied by an aplastic crisis due to parvovirus B19 infection. Parvovirus B19 infection causes diseases such as erythema infectiosum and arthritis, and can also trigger various autoimmune diseases, including autoimmune hemolytic anemia (AIHA). Here, we report a rare case of AIHA developing 3 months after an aplastic crisis due to parvovirus B19 infection in an 11-year-old boy with HS and provide the relevant literature review.
