Whole Mitochondrial Genome Sequence of an Indian Plasmodium falciparum Field Isolate.
- Author:
Suchi TYAGI
1
;
Veena PANDE
;
Aparup DAS
Author Information
- Publication Type:Brief Communication ; Research Support, Non-U.S. Gov't
- Keywords: Plasmodium falciparum; malaria; whole genome sequencing; mitochondrial genome; India
- MeSH: DNA, Mitochondrial/*chemistry/*genetics; Genetic Variation; *Genome, Mitochondrial; Humans; India; Malaria, Falciparum/parasitology; Molecular Sequence Data; Plasmodium falciparum/*genetics/isolation & purification; Sequence Analysis, DNA; Sequence Homology, Nucleic Acid
- From:The Korean Journal of Parasitology 2014;52(1):99-103
- CountryRepublic of Korea
- Language:English
- Abstract: Mitochondrial genome sequence of malaria parasites has served as a potential marker for inferring evolutionary history of the Plasmodium genus. In Plasmodium falciparum, the mitochondrial genome sequences from around the globe have provided important evolutionary understanding, but no Indian sequence has yet been utilized. We have sequenced the whole mitochondrial genome of a single P. falciparum field isolate from India using novel primers and compared with the 3D7 reference sequence and 1 previously reported Indian sequence. While the 2 Indian sequences were highly divergent from each other, the presently sequenced isolate was highly similar to the reference 3D7 strain.
