A Case of Invasive Pulmonary Aspergillosis with Direct Invasion of the Mediastinum and the Left Atrium in an Immunocompetent Patient.
- Author:
Kyu Hyun HAN
1
;
Jung Hyun KIM
;
Sun Young SHIN
;
Hye Yun JEONG
;
Ji Min CHU
;
Hak Su KIM
;
Daejin KIM
;
Minjung SHIM
;
Sang Ho CHO
;
Eun Kyung KIM
Author Information
- Publication Type:Case Report
- Keywords: Invasive Pulmonary Aspergillosis; Immunocompetence; Mediastinal Neoplasms; Heart Neoplasms
- MeSH: Aged; Antifungal Agents; Biopsy; Bronchi; Cardiac Tamponade; Diabetes Mellitus; Dyspnea; Echocardiography; Female; Heart; Heart Atria*; Heart Neoplasms; Humans; Hypertension; Hyphae; Immunocompetence; Invasive Pulmonary Aspergillosis*; Mediastinal Cyst; Mediastinal Neoplasms; Mediastinum*; Methenamine; Pathology; Thorax
- From:Tuberculosis and Respiratory Diseases 2014;77(1):28-33
- CountryRepublic of Korea
- Language:English
- Abstract: We report a case of invasive pulmonary aspergillosis invading the mediastinum and the left atrium. A 70-year-old woman was hospitalized for dyspnea. She had been well controlled for her diabetes mellitus and hypertension. The chest X-ray disclosed mediastinal widening, and the computed tomography scan of the chest showed that there was a large mediastinal mass and this lesion extended into the left atrium and right bronchus. The cardiac echocardiography showed that a huge mediastinal cystic mass compressed in the right atrium and a hyperechoic polypoid lesion in the left. The pathology from the bronchoscopic biopsy observed abundant fungal hyphae which was stained with periodic acid-Schiff and Gomori's methenamine silver. Despite the treatment with antifungal agents, she died from cardiac tamponade after three months. Invasive pulmonary aspergillosis, which involves the mediastinum and the heart, is very rare in immunocompetent patients.
