Post-transplant Lymphoproliferative Disorder in Transplanted Kidney Causing Urinary Tract Obstruction.
10.4285/jkstn.2016.30.1.44
- Author:
Hyeoncheol PARK
1
;
Jae Seok KIM
;
Jee Hyun KONG
;
Sung Hoon KIM
;
Sang Wook PARK
;
Shin Han SONG
;
Jae Won YANG
;
Byoung Geun HAN
;
Seung Ok CHOI
Author Information
1. Department of Nephrology, Yonsei University Wonju College of Medicine, Wonju, Korea. kidney77@yonsei.ac.kr
- Publication Type:Case Report
- Keywords:
Lymphoproliferative disorders;
Kidney transplantation;
Hydronephrosis
- MeSH:
Humans;
Hydronephrosis;
Immunosuppression;
Kidney Transplantation;
Kidney*;
Lymphoma;
Lymphoproliferative Disorders*;
Mortality;
Rituximab;
Transplants;
Urinary Tract*
- From:The Journal of the Korean Society for Transplantation
2016;30(1):44-49
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Post-transplant lymphoproliferative disorder (PTLD) is a serious complication resulting in mortality and renal graft failure. PTLD is a heterogeneous disorder, which causes different clinical forms of disease from non-specific viral syndrome to malignant lymphoma and has various etiologies, clinical features, and treatment strategies. Here, we report on a patient who had a PTLD in the hilum of a transplanted kidney at 5 months after renal transplantation. The PTLD resulted in hydronephrosis of the transplanted kidney and graft dysfunction by local urinary tract obstruction. Despite treatment including immunosuppression reduction and rituximab administration, we removed the transplanted kidney from the recipient because the PTLD did not respond to the therapy.