Bilateral Macular Infarction in Primary Antiphospholipid Syndrome.
10.3341/jkos.2017.58.10.1205
- Author:
Hyun Ju KIM
1
;
Han Gyul YOON
;
Seong Taeck KIM
Author Information
1. Department of Ophthalmology, Chosun University College of Medicine, Gwangju, Korea. s20age@hanmail.net
- Publication Type:Case Report
- Keywords:
Antiphospholipid syndrome;
Macular infarction
- MeSH:
Adult;
Antibodies, Antinuclear;
Antiphospholipid Syndrome*;
Cesarean Section;
Chorioamnionitis;
Diagnosis;
Female;
Fingers;
Hematologic Tests;
Humans;
Infarction*;
Lupus Coagulation Inhibitor;
Macular Edema;
Ophthalmology;
Pregnancy;
Rheumatoid Factor;
Thrombophilia;
Triamcinolone Acetonide;
Visual Acuity
- From:Journal of the Korean Ophthalmological Society
2017;58(10):1205-1210
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: We report a rare case of bilateral macular infarction as an ocular presenting sign of primary antiphospholipid syndrome. CASE SUMMARY: A 29-year-old woman who had undergone a cesarean section for chorioamnionitis in the department of Obsterics was referred to the department of ophthalmology for bilateral visual loss. At examination, best-corrected visual acuity (BCVA) of the right eye was counting fingers, and for the left was 0.05. Fundus examination revealed extensive macular edema and cotton-wool spots in both eyes. We performed hematologic tests including thrombophilia examination. Antinuclear antibody and rheumatoid factor were negative but lupus anticoagulant presented high titers on two occasions 12 weeks apart. She was administered sub-Tenon's injections of triamcinolone acetonide 50 mg/week in both eyes under the diagnosis of bilateral macular arteriolar occlusion in primary antiphospholipid syndrome. Her BCVA remained 0.025 in her right eye and improved to 0.125 in her left eye. CONCLUSIONS: Macular infarction is an uncommon but severe complication of antiphospholipid syndrome. Early and regular fundus exam in patients with antiphospholipid syndrome is necessary to avoid progression of severe ocular complications.
