A Case of Alzheimer's Disease Manifesting as Posterior Cortical Atrophy.
- Author:
Seong Hye CHOI
1
;
Duk Lyul NA
;
Choong Kun HA
;
Yeon Lim SUH
Author Information
1. Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine.
- Publication Type:Case Report
- Keywords:
Posterior cortical atrophy;
Alzheimer's disease;
Dementia, Balint syndrome
- MeSH:
Alzheimer Disease*;
Apraxias;
Atrophy*;
Biopsy;
Brain;
Dementia;
Female;
Gerstmann Syndrome;
Humans;
Magnetic Resonance Imaging;
Memory;
Middle Aged;
Prosopagnosia;
Temporal Lobe;
Writing
- From:Journal of the Korean Neurological Association
1999;17(6):886-890
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A subgroup of patients with progressive degenerative dementia that begins with higher visual dysfunction has been referred to as posterior cortical atrophy (PCA). A 55-year-old woman presented with progressive visual disturbance for 4 years, which was followed by geographical disorientation, impairment of writing and calculation, and memory distur-bance. Neuropsychological deficits were characterized by Balint syndrome, visuospatial dysfunction, prosopagnosia, Gerstmann syndrome and apraxia. Brain MRI showed mild diffuse atrophy. F18-FDG-PET disclosed bilateral occipi-totemporoparietal hypometabolism, more pronounced on the right. Biopsy from right temporal lobe revealed neu-ropathological findings consistent with Alzheimer's disease.