Respiratory Depression Induced by Intraarticular Morphine under Total Knee Replacement: A case report.
10.4097/kjae.2005.49.6.888
- Author:
Chung Hyun PARK
1
;
Ji Hoon KIM
;
Jae Jung KIM
;
Seung Ho KIM
;
Jong Yeon LEE
;
Kum Hee CHUNG
;
Min Gu KIM
Author Information
1. Department of Anesthesiology and Pain Medicine, Pochon CHA University College of Medicine, Pocheon, Korea. anesthpark@hanmail.net
- Publication Type:Case Report
- Keywords:
intraarticular administration;
morphine;
naloxone;
respiratory depression
- MeSH:
Arthroplasty, Replacement, Knee*;
Humans;
Injections, Intravenous;
Morphine*;
Naloxone;
Respiratory Insufficiency*
- From:Korean Journal of Anesthesiology
2005;49(6):888-891
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Intraarticular administration of morphine has good analgesic effect and satisfactory duration. It also shows less adverse effect of morphine than subarachnoid or epidural administration. However, high dose of morphine can cause long lasting respiratory depression. Although naloxone is effective in treatment of adverse effects of morphine, it has short duration of action. So repeating intravenous injections or continuous administration following bolus injection are recommended. We experienced a case of low dose continuous naloxone infusion for treatment of respiratory depression caused by iatraarticular morphine administration in total knee replacement surgery patient without affecting analgesic effect.
